Preheat an air fryer to 400°F for 5 minutes.
Place the chicken in a bowl and sprinkle with 2 tablespoons cornstarch, tossing to coat and combine well.
Put chicken in the air fryer. Spray with oil and cook for 8-9 minutes, shaking the basket once during cooking.
Meanwhile, prepare the sauce. Add and whisk together the orange juice and zest, brown sugar, honey, soy sauce, vinegar, red pepper flakes, garlic powder, and ginger to a medium saucepan set over medium-high heat.
Bring the sauce to a boil, then reduce to a simmer for 4-5 minutes, whisking occasionally.
While simmering, whisk together the remaining cornstarch and cold water in a small bowl and set aside.
Add the cornstarch slurry, whisking well, and cook for 1 additional minute until the sauce is thick. Remove the sauce from the heat.
Remove chicken from the air fryer and combine with sauce. Serve over rice, garnished with sesame seeds.